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BDBM50056716 CHEMBL3326962

SMILES: NC(CO)(CO)CO.CC(Oc1ccc2n(cc(CCc3ccccc3)c2c1)-c1ccccc1)C(O)=O

InChI Key: InChIKey=OTPBDHCEKFLZJL-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056716   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cPLA2 C2


(Homo sapiens (Human))
BDBM50056716
PNG
(CHEMBL3326962)
Show SMILES CC(Oc1ccc2n(cc(CCc3ccccc3)c2c1)-c1ccccc1)C(O)=O
Show InChI InChI=1/C25H23NO3.C4H11NO3/c1-18(25(27)28)29-22-14-15-24-23(16-22)20(13-12-19-8-4-2-5-9-19)17-26(24)21-10-6-3-7-11-21;5-4(1-6,2-7)3-8/h2-11,14-18H,12-13H2,1H3,(H,27,28);6-8H,1-3,5H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Asubio Pharma Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...


J Med Chem 57: 7244-62 (2014)


Article DOI: 10.1021/jm500494y
BindingDB Entry DOI: 10.7270/Q2F47QSP
More data for this
Ligand-Target Pair