BDBM50057034 CHEMBL3326128

SMILES COc1ccc(OC)c(Sc2ccc3nnc(-c4cnn(C)c4)n3n2)c1

InChI Key InChIKey=RAHGVIZTQAHVRX-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057034   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057034(CHEMBL3326128)
Affinity DataIC50:  64nMAssay Description:Inhibition of GST-tagged truncated LRRK2 (unknown origin) using fluorescein-labeled peptide LRRKtide as substrate by LANTHA screen assay in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057034(CHEMBL3326128)
Affinity DataIC50:  387nMAssay Description:Inhibition of phosphorylation at S935 residue of wild-type full-length LRRK2 kinase (unknown origin) expressed in HEK 293 cells after 90 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed