BDBM50057083 (R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pentan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)propanoic acid::(R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-3-phenyl-propylamino]-propionic acid::(R)-2-[(S)-1-(3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-3-phenyl-propylamino]-propionic acid::CHEMBL8494::L-696418

SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](C)C(O)=O)C(=O)Nc1ccccc1

InChI Key InChIKey=DLCYKLDSIUJNLE-COPCDDAFSA-N

Data  14 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50057083   

Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  200nMAssay Description:Inhibitory activity against human gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  200nMAssay Description:Inhibition of human gelatinase A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  200nMAssay Description:Inhibition of matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  200nMAssay Description:Inhibition of MMP-2.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  310nMAssay Description:Inhibition of human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  310nMAssay Description:Inhibition of matrix metalloproteinase-3(MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  468nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  470nMAssay Description:Inhibitory activity against human stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  470nMAssay Description:Inhibition of MMP-3.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  470nMAssay Description:Inhibition of human fibroblast stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  760nMAssay Description:Inhibition of matrix metalloproteinase -1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  760nMAssay Description:Inhibitory activity against human collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  760nMAssay Description:Inhibition of human fibroblast collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  770nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity against Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article