BDBM50057165 3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-isoquinolin-1-ylmethyl-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10860

SMILES COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1nccc2ccccc12)c1ccc2OCOc2c1

InChI Key InChIKey=AFZSZVWTPJVSMZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057165   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057165(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-isoquinolin-1-...)
Affinity DataIC50:  10nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057165(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-isoquinolin-1-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Binding affinity against human cloned Endothelin B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed