BDBM50057386 Analog of Dynorphin A::CHEMBL263366

SMILES CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(=O)N[C@@H](CCNC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=ATJBGHAJWAUIGB-HUCZMNRHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057386   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50057386(Analog of Dynorphin A | CHEMBL263366)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to Opioid receptor kappa 1 by competitive inhibition of radioligand [3H]-diprenorphine using cloned receptors transiently expressed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50057386(Analog of Dynorphin A | CHEMBL263366)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to Opioid receptor mu 1 by competitive inhibition of radioligand [3H]-DAMGO using cloned receptors transiently expressed on CHO cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50057386(Analog of Dynorphin A | CHEMBL263366)
Affinity DataKi:  180nMAssay Description:Binding affinity to Opioid receptor delta 1 by competitive inhibition of radioligand [3H]-DPDPE using cloned receptors transiently expressed on CHO c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed