BDBM50057460 4-(3-{4-[(R)-1-(4-Isobutyl-phenyl)-ethoxy]-benzoyl}-indol-1-yl)-butyric acid::CHEMBL280954

SMILES CC(C)Cc1ccc(cc1)[C@@H](C)Oc1ccc(cc1)C(=O)c1cn(CCCC(O)=O)c2ccccc12

InChI Key InChIKey=SMSOYFGWXDACGL-JOCHJYFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057460   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057460(4-(3-{4-[(R)-1-(4-Isobutyl-phenyl)-ethoxy]-benzoyl...)
Affinity DataIC50:  574nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057460(4-(3-{4-[(R)-1-(4-Isobutyl-phenyl)-ethoxy]-benzoyl...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human 5-alpha reductase 2 isozyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed