BDBM50057463 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-isopropyl-6-methoxy-phenoxy)-ethanone::CHEMBL430717
SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)COc1c(OC)cccc1C(C)C
InChI Key InChIKey=ZZMFJJDBKSYGRM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50057463
Affinity DataKi: 0.450nMAssay Description:The binding affinity of the compound was determined towards Alpha-1B adrenergic receptor in the COS cell line.More data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:The binding affinity of the compound was determined towards Alpha-1A adrenergic receptor in the COS cell line.More data for this Ligand-Target Pair
Affinity DataKi: 10.3nMAssay Description:The binding affinity of the compound was determined towards Alpha-1C adrenergic receptor in the COS cell line.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2A receptor (Inactive at >1000 nM concentration)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Binding affinity was tested on cloned hamster Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against Dopamine receptor D2 (Inactive at >1000 nM concentration)More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Binding affinity was tested on cloned rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Binding affinity was tested on cloned bovine Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor (Inactive at >1000 nM concentration)More data for this Ligand-Target Pair