BDBM50057470 4-{3-[2,2-Bis-(4-chloro-phenyl)-benzo[1,3]dioxole-5-carbonyl]-2-methyl-indol-1-yl}-butyric acid::CHEMBL285439

SMILES Cc1c(C(=O)c2ccc3OC(Oc3c2)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)c2ccccc2n1CCCC(O)=O

InChI Key InChIKey=SWSOLWZGKLCZDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057470   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057470(4-{3-[2,2-Bis-(4-chloro-phenyl)-benzo[1,3]dioxole-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057470(4-{3-[2,2-Bis-(4-chloro-phenyl)-benzo[1,3]dioxole-...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human 5-alpha reductase 2 isozyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed