BDBM50057499 (R)-8-Chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::CHEMBL417109

SMILES CN1C2CCc3cc(Cl)ccc3[C@@]2(C)CCC1=O

InChI Key InChIKey=KTBSRSVHEOTHLD-AWKYBWMHSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057499   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057499((R)-8-Chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahyd...)
Affinity DataKi:  9nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057499((R)-8-Chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahyd...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057499((R)-8-Chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahyd...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed