BDBM50057511 (+/-)-indolactum-V 13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraen-11-one::(-)-indolactam V::(10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4(15),5,7-tetraen-11-one::(10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraen-11-one::(2S,5S)-5-(hydroxymethyl)-2-isopropyl-1-methyl-1,2,5,6-tetrahydro-4H-[1,4]diazonino[7,6,5-cd]indol-3(8H)-one::(S)-13-Hydroxymethyl-10-isopropyl-9-(S)-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraen-11-one::13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4(15),5,7-tetraen-11-one::13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraen-11-one(ILV)::CHEMBL27266::INDOLACTUM::indolactam-V

SMILES: CC(C)[C@H]1C(=O)N[C@@H](Cc2c[nH]c3c2c(ccc3)N1C)CO

InChI Key: InChIKey=LUZOFMGZMUZSSK-UHFFFAOYSA-N

Data: 70 KI  1 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 73 hits for monomerid = 50057511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C gamma type (Rat)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		2.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		2.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		2.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Rat)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		2.54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C eta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C eta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C eta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C eta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		10.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		10.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		19.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		21.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		25.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		25.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		66.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Mouse)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		66.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50057511 (CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair