BDBM50057526 4-[3-Difluoromethyl-5-(4-methanesulfonyl-phenyl)-pyrazol-1-yl]-benzenesulfonamide::CHEMBL28084

SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)F

InChI Key InChIKey=WQKRRUDWJUIGNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057526   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057526(4-[3-Difluoromethyl-5-(4-methanesulfonyl-phenyl)-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057526(4-[3-Difluoromethyl-5-(4-methanesulfonyl-phenyl)-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed