BDBM50057593 4-[5-(4-Chloro-phenyl)-3-(4-methoxy-phenyl)-pyrazol-1-yl]-benzenesulfonamide::CHEMBL29423

SMILES COc1ccc(cc1)-c1cc(-c2ccc(Cl)cc2)n(n1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=RDVMVFHKIXFZDK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057593   

TargetProstaglandin G/H synthase 2(Human)
Leibniz Institute For Plasma Science and Technology (Inp Greifswald)

Curated by ChEMBL
LigandPNGBDBM50057593(4-[5-(4-Chloro-phenyl)-3-(4-methoxy-phenyl)-pyrazo...)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human COX-2 by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Leibniz Institute For Plasma Science and Technology (Inp Greifswald)

Curated by ChEMBL
LigandPNGBDBM50057593(4-[5-(4-Chloro-phenyl)-3-(4-methoxy-phenyl)-pyrazo...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057593(4-[5-(4-Chloro-phenyl)-3-(4-methoxy-phenyl)-pyrazo...)
Affinity DataIC50: 8.49E+3nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed