BDBM50057611 1,5-Bis-(4-chloro-phenyl)-3-trifluoromethyl-1H-pyrazole::CHEMBL284914

SMILES FC(F)(F)c1cc(-c2ccc(Cl)cc2)n(n1)-c1ccc(Cl)cc1

InChI Key InChIKey=JINJJDHGBJMQJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057611   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057611(1,5-Bis-(4-chloro-phenyl)-3-trifluoromethyl-1H-pyr...)
Affinity DataIC50: 55nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057611(1,5-Bis-(4-chloro-phenyl)-3-trifluoromethyl-1H-pyr...)
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057611(1,5-Bis-(4-chloro-phenyl)-3-trifluoromethyl-1H-pyr...)
Affinity DataIC50: 4.79E+3nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed