BDBM50057875 3-[1-(4-Acetyl-phenyl)-5-(4-methoxy-phenyl)-1H-pyrrol-2-yl]-propionic acid::CHEMBL43664

SMILES COc1ccc(cc1)-c1ccc(CCC(O)=O)n1-c1ccc(cc1)C(C)=O

InChI Key InChIKey=VJZKDNLUHNLJEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057875   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057875(3-[1-(4-Acetyl-phenyl)-5-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in retinoic acid stimulated HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057875(3-[1-(4-Acetyl-phenyl)-5-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 in IL-1-stimulated dermal fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057875(3-[1-(4-Acetyl-phenyl)-5-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057875(3-[1-(4-Acetyl-phenyl)-5-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed