BDBM50057882 2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrol-3-yl]-ethanone::CHEMBL42409

SMILES Cc1c(cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccc(F)cc1)C(=O)C(F)(F)F

InChI Key InChIKey=DITSXUUEJDNZAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057882   

TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057882(2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057882(2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057882(2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed