BDBM50058137 2-(2-p-Tolyl-acetyl)-thiophene-3-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL45875

SMILES Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc(C)cc2)c1C

InChI Key InChIKey=BGVMHOXNOKQCIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058137   

TargetEndothelin receptor type B(Homo sapiens (Human))
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058137(2-(2-p-Tolyl-acetyl)-thiophene-3-sulfonic acid (3,...)
Affinity DataIC50:  2.92E+4nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058137(2-(2-p-Tolyl-acetyl)-thiophene-3-sulfonic acid (3,...)
Affinity DataIC50:  27nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed