BDBM50058212 9-(2-fluorobenzyl)-N-methyl-2-(trifluoromethyl)-9H-purin-6-amine::CHEMBL299650::[9-(2-Fluoro-benzyl)-2-trifluoromethyl-9H-purin-6-yl]-methyl-amine

SMILES CNc1nc(nc2n(Cc3ccccc3F)cnc12)C(F)(F)F

InChI Key InChIKey=QWECFCKUHAMUOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058212   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50058212(9-(2-fluorobenzyl)-N-methyl-2-(trifluoromethyl)-9H...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant PDE4B using cAMP as substrate incubated for 20 mins measured by Kinase Glo reagent based microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Upr 421 Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50058212(9-(2-fluorobenzyl)-N-methyl-2-(trifluoromethyl)-9H...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed