BDBM50058452 1-(4-Chloro-phenyl)-2-methyl-isothiourea; hydriodide::CHEMBL538001::N-(4-Chlorophenyl)-S-methylisothiourea hydroiodide

SMILES CSC(N)=Nc1ccc(Cl)cc1

InChI Key InChIKey=RVVNEQQMDNKLRB-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50058452   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50058452(1-(4-Chloro-phenyl)-2-methyl-isothiourea; hydriodi...)
Affinity DataKi:  570nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase in brain (nNOS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50058452(1-(4-Chloro-phenyl)-2-methyl-isothiourea; hydriodi...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibitory activity against human vascular endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50058452(1-(4-Chloro-phenyl)-2-methyl-isothiourea; hydriodi...)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibitory activity against human inducible nitric oxide synthase (iNOS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50058452(1-(4-Chloro-phenyl)-2-methyl-isothiourea; hydriodi...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of indoleamine-2,3-dioxygenase in human A431 cells assessed as inhibition of IFN-gamma-stimulated kynurenine productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50058452(1-(4-Chloro-phenyl)-2-methyl-isothiourea; hydriodi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of indoleamine-2,3-dioxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed