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BDBM50058583 CHEMBL59901::N-{[[1-(1-benzothien-2-yl)ethyl](hydroxy)amino]carbonyl}acetamide

SMILES: CC(N(O)C(=O)NC(C)=O)c1cc2ccccc2s1

InChI Key: InChIKey=ONAFXCMLXCRAGO-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058583   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50058583
PNG
(CHEMBL59901 | N-{[[1-(1-benzothien-2-yl)ethyl](hyd...)
Show SMILES CC(N(O)C(=O)NC(C)=O)c1cc2ccccc2s1
Show InChI InChI=1/C13H14N2O3S/c1-8(15(18)13(17)14-9(2)16)12-7-10-5-3-4-6-11(10)19-12/h3-8,18H,1-2H3,(H,14,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE production


J Med Chem 40: 1955-68 (1997)


Article DOI: 10.1021/jm9700474
BindingDB Entry DOI: 10.7270/Q2NV9JWT
More data for this
Ligand-Target Pair