BDBM50058978 3-(4-Chloro-benzenesulfonyl)-1-[4-(4-methyl-piperazine-1-carbonyl)-phenyl]-imidazolidine-2,4-dione::CHEMBL68162

SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)N1CC(=O)N(C1=O)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=FPCATIWUNJFGBZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058978   

TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058978(3-(4-Chloro-benzenesulfonyl)-1-[4-(4-methyl-pipera...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058978(3-(4-Chloro-benzenesulfonyl)-1-[4-(4-methyl-pipera...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058978(3-(4-Chloro-benzenesulfonyl)-1-[4-(4-methyl-pipera...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed