BDBM50058984 3-(3,4-Dichloro-benzenesulfonyl)-1-(3,4-dimethyl-phenyl)-imidazolidine-2,4-dione::CHEMBL442366

SMILES Cc1ccc(cc1C)N1CC(=O)N(C1=O)S(=O)(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=WRXQRIDLDWGZSK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058984   

TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058984(3-(3,4-Dichloro-benzenesulfonyl)-1-(3,4-dimethyl-p...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058984(3-(3,4-Dichloro-benzenesulfonyl)-1-(3,4-dimethyl-p...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058984(3-(3,4-Dichloro-benzenesulfonyl)-1-(3,4-dimethyl-p...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed