BDBM50059097 5-Methyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one::CHEMBL49267

SMILES Cc1ccc(cc1)-c1cc(O)c2c(C)ccnc2n1

InChI Key InChIKey=YMGBUMKFZOUPGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059097   

TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059097(5-Methyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one | CH...)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059097(5-Methyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one | CH...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed