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BDBM50059379 4-Furan-2-yl-2-methyl-6-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester::CHEMBL89797

SMILES: CCOC(=O)C1C(c2ccco2)C(C(=O)OCC)=C(N=C1C)c1ccccc1

InChI Key: InChIKey=QWVJJNOXMJFLIF-UHFFFAOYNA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059379   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50059379
PNG
(4-Furan-2-yl-2-methyl-6-phenyl-1,4-dihydro-pyridin...)
Show SMILES CCOC(=O)C1C(c2ccco2)C(C(=O)OCC)=C(N=C1C)c1ccccc1
Show InChI InChI=1/C22H23NO5/c1-4-26-21(24)17-14(3)23-20(15-10-7-6-8-11-15)19(22(25)27-5-2)18(17)16-12-9-13-28-16/h6-13,17-18H,4-5H2,1-3H3
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
507n/an/an/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor.


J Med Chem 40: 2596-608 (1997)


Article DOI: 10.1021/jm970091j
BindingDB Entry DOI: 10.7270/Q21V5D29
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50059379
PNG
(4-Furan-2-yl-2-methyl-6-phenyl-1,4-dihydro-pyridin...)
Show SMILES CCOC(=O)C1C(c2ccco2)C(C(=O)OCC)=C(N=C1C)c1ccccc1
Show InChI InChI=1/C22H23NO5/c1-4-26-21(24)17-14(3)23-20(15-10-7-6-8-11-15)19(22(25)27-5-2)18(17)16-12-9-13-28-16/h6-13,17-18H,4-5H2,1-3H3
PDB

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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.54E+4n/an/an/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Displacement of specific [3H]-(R)-PIA binding at adenosine A1 receptor from rat brain membranes.


J Med Chem 40: 2596-608 (1997)


Article DOI: 10.1021/jm970091j
BindingDB Entry DOI: 10.7270/Q21V5D29
More data for this
Ligand-Target Pair