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BDBM50059574 7-Fluoro-2-(3-methoxy-phenyl)-2,3-dihydro-1H,10H-phenothiazin-4-one::CHEMBL93465

SMILES: COc1cccc(c1)C1CC(=O)C2Sc3cc(F)ccc3N=C2C1

InChI Key: InChIKey=BIYZSUOXHGMACH-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059574   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Falcipain-2


(Plasmodium falciparum)
BDBM50059574
PNG
(7-Fluoro-2-(3-methoxy-phenyl)-2,3-dihydro-1H,10H-p...)
Show SMILES COc1cccc(c1)C1CC(=O)C2Sc3cc(F)ccc3N=C2C1
Show InChI InChI=1/C19H16FNO2S/c1-23-14-4-2-3-11(7-14)12-8-16-19(17(22)9-12)24-18-10-13(20)5-6-15(18)21-16/h2-7,10,12,19H,8-9H2,1H3
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Universidad Central de Venezuela

Curated by ChEMBL


Assay Description
Inhibition of falcipain activity


J Med Chem 40: 2726-32 (1997)


Article DOI: 10.1021/jm970266p
BindingDB Entry DOI: 10.7270/Q2HX1BSD
More data for this
Ligand-Target Pair