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BDBM50059580 7-Chloro-2,2-dimethyl-2,3-dihydro-1H,10H-phenothiazin-4-one::CHEMBL92872

SMILES: CC1(C)CC(=O)C2Sc3cc(Cl)ccc3N=C2C1

InChI Key: InChIKey=CZNNCJATYPVYTO-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059580   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Falcipain-2


(Plasmodium falciparum)
BDBM50059580
PNG
(7-Chloro-2,2-dimethyl-2,3-dihydro-1H,10H-phenothia...)
Show SMILES CC1(C)CC(=O)C2Sc3cc(Cl)ccc3N=C2C1
Show InChI InChI=1/C14H14ClNOS/c1-14(2)6-10-13(11(17)7-14)18-12-5-8(15)3-4-9(12)16-10/h3-5,13H,6-7H2,1-2H3
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



Universidad Central de Venezuela

Curated by ChEMBL


Assay Description
Inhibition of falcipain activity


J Med Chem 40: 2726-32 (1997)


Article DOI: 10.1021/jm970266p
BindingDB Entry DOI: 10.7270/Q2HX1BSD
More data for this
Ligand-Target Pair