BDBM50059659 CHEMBL3393604

SMILES COc1ccc2OC(COc2c1)C(=O)NC(=O)N(CC(C)C)CC(=O)NCCCCCCNC(=O)c1ccc(cc1)-c1n[nH]c2ccccc12

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059659   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50:  99nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of JNK3-mediated c-jun phosphorylation in rat INS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50:  336nMAssay Description:Inhibition of JNK2 (unknown origin) by JIP-FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50:  109nMAssay Description:Inhibition of JNK1 (unknown origin) by JIP-FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50:  12nMAssay Description:Inhibition of JNK3 (unknown origin) by JIP-FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed