BDBM50059813 CHEMBL98691::{4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-phenyl}-piperidin-1-yl-methanone

SMILES COc1cccc(c1)[C@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccc(cc1)C(=O)N1CCCCC1

InChI Key InChIKey=ZMVFPDSYCFNQEK-AWVRMFGXSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059813   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059813(CHEMBL98691 | {4-[(R)-((2S,5R)-4-Allyl-2,5-dimethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for Opioid receptor kappa 1 by the inhibition of binding of [3H]U-69593 in guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059813(CHEMBL98691 | {4-[(R)-((2S,5R)-4-Allyl-2,5-dimethy...)
Affinity DataIC50:  38nMAssay Description:Binding affinity for Opioid receptor delta 1 by the inhibition of binding of [3H]-p-DPDPE human cloned receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059813(CHEMBL98691 | {4-[(R)-((2S,5R)-4-Allyl-2,5-dimethy...)
Affinity DataIC50: >2.50E+3nMAssay Description:Binding affinity for Opioid receptor mu 1 by the inhibition of binding of [3H]DAMGO in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059813(CHEMBL98691 | {4-[(R)-((2S,5R)-4-Allyl-2,5-dimethy...)
Affinity DataIC50:  15nMAssay Description:Binding affinity for Opioid receptor delta 1 by the inhibition of binding of [3H]DADAL in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059813(CHEMBL98691 | {4-[(R)-((2S,5R)-4-Allyl-2,5-dimethy...)
Affinity DataIC50:  6.00E+3nMAssay Description:Binding affinity for micro receptors by the inhibition of binding of [3H]DAMGO to Opioid receptor mu 1 in human cloned receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed