BDBM50059891 1-amino-2-(3,4,5-trimethoxyphenyl)ethane::2-(3,4,5-trimethoxyphenyl)ethanamine::3,4,5-trimethoxybenzeneethanamine::3,4,5-trimethoxyphenethylamine::3,4,5-trimethoxyphenylethylamine::CHEMBL26687::Mescalin::Meskalin::TMPEA::mescalina::mescaline::mezcalina

SMILES COc1cc(CCN)cc(OC)c1OC

InChI Key InChIKey=RHCSKNNOAZULRK-UHFFFAOYSA-N

Data  10 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50059891   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  303nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  360nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  380nMAssay Description:Displacement of [125I]DOI from rat 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  551nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  795nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  5.50E+3nMAssay Description:Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  5.50E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  6.90E+3nMAssay Description:Ability to displace [3H]-8-OH-DPAT from rat hippocampal homogenate 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(BOVINE)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataEC50:  1.13E+4nMAssay Description:Activity at rat 5HT2A receptor assessed as 5HT-stimulated IP3 accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataEC50:  2.60E+3nMAssay Description:Tested for its ability to activate phospholipase c by quantification of IP3 at cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataEC50:  2.40E+4nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataEC50:  4.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed