BDBM50059925 8-[(3,4,5-Trimethoxy-phenylamino)-methyl]-9H-purine-2,6-diamine::CHEMBL102444

SMILES COc1cc(NCc2nc3nc(N)nc(N)c3[nH]2)cc(OC)c1OC

InChI Key InChIKey=VOUIYXLUJHGZHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059925   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059925(8-[(3,4,5-Trimethoxy-phenylamino)-methyl]-9H-purin...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059925(8-[(3,4,5-Trimethoxy-phenylamino)-methyl]-9H-purin...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059925(8-[(3,4,5-Trimethoxy-phenylamino)-methyl]-9H-purin...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed