BDBM50060600 (S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)-4-methyl-pentanoic acid carbamoylmethyl-amide::CHEMBL332740

SMILES CC(C)C[C@H](N1CC(=O)N2CCC[C@H]2C1=O)C(=O)NCC(N)=O

InChI Key InChIKey=DNVVWPSQSKLWQF-QWRGUYRKSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50060600   

TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060600((S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyraz...)
Affinity DataKi:  0.0680nMAssay Description:Percentage of receptor in the high affinity form for the compound to Dopamine receptor D2 in presence of Gpp(NH)p (pretreated with 100 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060600((S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyraz...)
Affinity DataKi:  0.0800nMAssay Description:Inhibitory constant of compound in absence of Gpp(NH)p calculated for the high affinity components of the [3H]spiroperidol binding to Dopamine recept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060600((S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyraz...)
Affinity DataKi:  0.0800nMAssay Description:Inhibitory constant of compound in presence of Gpp(NH)p (Pre treated with 100 nM) calculated for the high affinity components of the [3H]spiroperidol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060600((S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyraz...)
Affinity DataKi:  0.120nMAssay Description:Inhibitory constant of compound in presence of Gpp(NH)p calculated for the high affinity components of the [3H]spiroperidol binding to Dopamine recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060600((S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyraz...)
Affinity DataKi:  91nMAssay Description:Inhibitory constant of compound in absence of Gpp(NH)p (Pretreated with 100 nM) calculated for the high affinity components of the [3H]spiroperidol b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060600((S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyraz...)
Affinity DataKi:  104nMAssay Description:Inhibitory constant of compound in presence of Gpp(NH)p (Pre treated with 100 nM) calculated for the low affinity components of the [3H]spiroperidol ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060600((S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyraz...)
Affinity DataKi:  120nMAssay Description:Inhibitory constant of compound in absence of Gpp(NH)p calculated for the low affinity components of the [3H]spiroperidol binding to Dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060600((S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyraz...)
Affinity DataKi:  172nMAssay Description:Inhibitory constant of compound in presence of Gpp(NH)p calculated for the low affinity components of the [3H]spiroperidol binding to Dopamine recept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed