BDBM50060688 7-Fluoro-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinoxaline::7-fluoro-4-(4-methylpiperazin-1-yl)pyrrolo[1,2-a]quinoxaline::CHEMBL341474
SMILES CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12
InChI Key InChIKey=RYXJSAHVNPQLMV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50060688
Target5-hydroxytryptamine receptor 3A(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 0.810nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 124nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 138nMAssay Description:Displacement of [3H]8-OHDPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataIC50: 124nMAssay Description:Inhibition of radiolabeled [3H]-Ketanserin ligand binding to 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of radiolabeled [3H]GR-113808 ligand binding to 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 413nMAssay Description:Inhibition of radiolabeled [3H]mesulergine ligand binding to 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 371nMAssay Description:Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Agonist activity at 5HT3 receptor in voltage-stimulated guinea pig left atrium assessed as positive inotropic potencyMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Homo sapiens (Human))
Universita' Degli Studi Di Salerno
Curated by ChEMBL
Universita' Degli Studi Di Salerno
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]-guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of radiolabeled [3H]-8-OH-DPAT ligand binding to 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair