BDBM50060735 2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-carboxy-butyrylamino}-4-carboxy-butyrylamino)-3-methyl-pentanoylamino]-pentanedioic acid::CHEMBL299477

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=QQEKQSBIEKQXQS-PSCZMIBCSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50060735   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  500nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  2.00E+3nMAssay Description:Affinity for GST- Src-SH2 domain in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Mogam Biotechnology Research Institute

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  1.10E+3nMAssay Description:Affinity for GST-Fyn-SH2 domain in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  7.90E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  500nMAssay Description:Inhibition of [125I]-phosphopeptide binding to Src SH2 domain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Mogam Biotechnology Research Institute

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of binding to p56 Lck tyrosine kinase SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  2.80E+3nMAssay Description:Binding affinity to p60 src SH2 domain.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Mogam Biotechnology Research Institute

Curated by ChEMBL
LigandPNGBDBM50060735(2-[2-(2-{2-[(S)-2-Acetylamino-3-(4-phosphonooxy-ph...)
Affinity DataIC50:  1.30E+3nMAssay Description:Affinity for GST-Lck-SH2 domain in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed