BDBM50061317 CHEMBL28115::N-(1,2,3,4-Tetrahydro-isoquinolin-7-ylmethyl)-methanesulfonamide

SMILES CS(=O)(=O)NCc1ccc2CCNCc2c1

InChI Key InChIKey=UMOYIPAUEYZTAT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50061317   

LigandPNGBDBM50061317(CHEMBL28115 | N-(1,2,3,4-Tetrahydro-isoquinolin-7-...)
Affinity DataKi:  8.74E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50061317(CHEMBL28115 | N-(1,2,3,4-Tetrahydro-isoquinolin-7-...)
Affinity DataKi:  3.08E+4nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50061317(CHEMBL28115 | N-(1,2,3,4-Tetrahydro-isoquinolin-7-...)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of Phenylethanolamine N-methyltransferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50061317(CHEMBL28115 | N-(1,2,3,4-Tetrahydro-isoquinolin-7-...)
Affinity DataKi:  3.30E+5nMAssay Description:In vitro inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed