BDBM50061430 CHEMBL335161::[4-(8-Chloro-5-hydroxy-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(1-oxy-pyridin-4-yl)-methanone

SMILES [#8]-[#6]-1-[#6]-c2cc(Cl)ccc2\[#6](=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-c2cc[n+](-[#8-])cc2)-c2ncccc-12

InChI Key InChIKey=OPGNDZTULVSXFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061430   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061430([4-(8-Chloro-5-hydroxy-5,6-dihydro-benzo[5,6]cyclo...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed