BDBM50061652 2-Propylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135636

SMILES CCCNCC1CCc2ccc(O)cc2O1

InChI Key InChIKey=PEHTUJKNDCNRDK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50061652   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061652(2-Propylaminomethyl-chroman-7-ol; oxalic acid | CH...)
Affinity DataKi:  6.90nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061652(2-Propylaminomethyl-chroman-7-ol; oxalic acid | CH...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Sprague-Dawley rat striatal membranes after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061652(2-Propylaminomethyl-chroman-7-ol; oxalic acid | CH...)
Affinity DataKi:  96nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061652(2-Propylaminomethyl-chroman-7-ol; oxalic acid | CH...)
Affinity DataKi:  177nMAssay Description:In vitro binding affinity to rat hippocampal 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50061652(2-Propylaminomethyl-chroman-7-ol; oxalic acid | CH...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampus membrane homogenates by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed