BDBM50061706 (1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]-acetonitrile::CHEMBL344892

SMILES CO\N=C(/C#N)C12CCN(CC1)C2

InChI Key InChIKey=LRXMLERJAJTUBK-DHZHZOJOSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50061706   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50:  1.65E+3nMAssay Description:In vitro affinity against human Muscarinic acetylcholine receptor M1 using quinuclidynyl benzylate (QNB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50:  240nMAssay Description:In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50:  1.95E+3nMAssay Description:In vitro inhibition of [3H]quinuclidinyl benzilate (QNB) binding to muscarinic receptors of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50:  300nMAssay Description:In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of oxotremorine-M (OXO-M) binding to muscarinic receptors of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50:  495nMAssay Description:In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed