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BDBM50061716 CHEMBL3394202

SMILES: COc1cc(C(N)=O)c(CC(=O)N2CCC3(CN(C3)[C@@H]3CCc4cc(ccc34)-c3nccc(C)n3)CC2)cn1

InChI Key: InChIKey=AOKZCDRMHWHQCF-RUZDIDTESA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061716   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))
BDBM50061716
PNG
(CHEMBL3394202)
Show SMILES COc1cc(C(N)=O)c(CC(=O)N2CCC3(CN(C3)[C@@H]3CCc4cc(ccc34)-c3nccc(C)n3)CC2)cn1
Show InChI InChI=1S/C30H34N6O3/c1-19-7-10-32-29(34-19)21-3-5-23-20(13-21)4-6-25(23)36-17-30(18-36)8-11-35(12-9-30)27(37)14-22-16-33-26(39-2)15-24(22)28(31)38/h3,5,7,10,13,15-16,25H,4,6,8-9,11-12,14,17-18H2,1-2H3,(H2,31,38)/t25-/m1/s1
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
263n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]Ghrelin from human GHS-R1a expressed in HEK293 cells after 8 hrs by SPA method


ACS Med Chem Lett 6: 156-61 (2015)


Article DOI: 10.1021/ml500414n
BindingDB Entry DOI: 10.7270/Q2N58P10
More data for this
Ligand-Target Pair