BindingDB logo
myBDB logout

BDBM50062143 6-Cyclohexyl-piperidin-(2Z)-ylideneamine::CHEMBL7133

SMILES: NC1=NC(CCC1)C1CCCCC1

InChI Key: InChIKey=IWONLBSAXYOQRL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062143   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50062143
PNG
(6-Cyclohexyl-piperidin-(2Z)-ylideneamine | CHEMBL7...)
Show SMILES NC1=NC(CCC1)C1CCCCC1
Show InChI InChI=1S/C11H20N2/c12-11-8-4-7-10(13-11)9-5-2-1-3-6-9/h9-10H,1-8H2,(H2,12,13)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 8.70E+3n/an/an/an/an/an/a



G. D. Searle Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human Inducible nitric oxide synthase


J Med Chem 41: 96-101 (1998)


Article DOI: 10.1021/jm9705059
BindingDB Entry DOI: 10.7270/Q2GM86D2
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50062143
PNG
(6-Cyclohexyl-piperidin-(2Z)-ylideneamine | CHEMBL7...)
Show SMILES NC1=NC(CCC1)C1CCCCC1
Show InChI InChI=1S/C11H20N2/c12-11-8-4-7-10(13-11)9-5-2-1-3-6-9/h9-10H,1-8H2,(H2,12,13)
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



G. D. Searle Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human Neuronal nitric oxide synthase


J Med Chem 41: 96-101 (1998)


Article DOI: 10.1021/jm9705059
BindingDB Entry DOI: 10.7270/Q2GM86D2
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50062143
PNG
(6-Cyclohexyl-piperidin-(2Z)-ylideneamine | CHEMBL7...)
Show SMILES NC1=NC(CCC1)C1CCCCC1
Show InChI InChI=1S/C11H20N2/c12-11-8-4-7-10(13-11)9-5-2-1-3-6-9/h9-10H,1-8H2,(H2,12,13)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.42E+5n/an/an/an/an/an/a



G. D. Searle Research and Development

Curated by ChEMBL


Assay Description
inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)


J Med Chem 41: 96-101 (1998)


Article DOI: 10.1021/jm9705059
BindingDB Entry DOI: 10.7270/Q2GM86D2
More data for this
Ligand-Target Pair