BDBM50062324 (2R,3S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((R)-3-methyl-1-methylcarbamoyl-butyl)-succinamide::CHEMBL70398

SMILES CNC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO

InChI Key InChIKey=OKGPERFMUXABQD-UTUOFQBUSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062324   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062324((2R,3S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((R)-3-me...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062324((2R,3S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((R)-3-me...)
Affinity DataKi:  0.530nMAssay Description:The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062324((2R,3S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((R)-3-me...)
Affinity DataKi:  2.30nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed