BDBM50062351 (R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide::(R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide::(R)-N1-((S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide::3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE::CHEMBL19611::Ilomastat::US9487462, ilomastat

SMILES: CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO

InChI Key: InChIKey=NITYDPDXAAFEIT-UHFFFAOYSA-N

Data: 17 KI  93 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 110 hits for monomerid = 50062351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.177	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.422	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.104	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.191	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-15 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-26 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-16 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 10 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 9 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 12 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.93	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-16 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-26 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-15 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrilysin (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil collagenase (Human)	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair