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BDBM50062518 (S)-2-[(R)-1-Amino-1-carboxy-3-(3-chloro-phenyl)-propyl]-cyclopropanecarboxylic acid::CHEMBL333771

SMILES: N[C@](CCc1cccc(Cl)c1)(C1C[C@@H]1C(O)=O)C(O)=O

InChI Key: InChIKey=GUTXZRKRYGCMAD-PFSRQVJMSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062518   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50062518
PNG
((S)-2-[(R)-1-Amino-1-carboxy-3-(3-chloro-phenyl)-p...)
Show SMILES N[C@](CCc1cccc(Cl)c1)(C1C[C@@H]1C(O)=O)C(O)=O
Show InChI InChI=1S/C14H16ClNO4/c15-9-3-1-2-8(6-9)4-5-14(16,13(19)20)11-7-10(11)12(17)18/h1-3,6,10-11H,4-5,7,16H2,(H,17,18)(H,19,20)/t10-,11?,14+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 180n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 2


J Med Chem 41: 358-78 (1998)


Article DOI: 10.1021/jm970498o
BindingDB Entry DOI: 10.7270/Q2XP7423
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Homo sapiens (Human))
BDBM50062518
PNG
((S)-2-[(R)-1-Amino-1-carboxy-3-(3-chloro-phenyl)-p...)
Show SMILES N[C@](CCc1cccc(Cl)c1)(C1C[C@@H]1C(O)=O)C(O)=O
Show InChI InChI=1S/C14H16ClNO4/c15-9-3-1-2-8(6-9)4-5-14(16,13(19)20)11-7-10(11)12(17)18/h1-3,6,10-11H,4-5,7,16H2,(H,17,18)(H,19,20)/t10-,11?,14+/m0/s1
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 180n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 3


J Med Chem 41: 358-78 (1998)


Article DOI: 10.1021/jm970498o
BindingDB Entry DOI: 10.7270/Q2XP7423
More data for this
Ligand-Target Pair