BDBM50062614 CHEMBL900::Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine::Disipal::Invagesic::N,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanamine::Norflex::Norgesic::ORPHENADRINE::Orphengesic

SMILES: CN(C)CCOC(c1ccccc1)c1ccccc1C

InChI Key: InChIKey=QVYRGXJJSLMXQH-UHFFFAOYSA-N

Data: 10 KI  15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50062614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 2 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	851	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Rat)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 2 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 1 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Rat)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		40.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor (Rabbit)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		81.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Rat)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		97.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M5 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Rat)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		213	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Chicken)	BDBM50062614 (Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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