BDBM50062658 3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbonyl)-amino]-5-trifluoromethyl-benzoic acid ethyl ester::CHEMBL134490

SMILES CCOC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F

InChI Key InChIKey=CLAOSCDDLTTWAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062658   

TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062658(3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...)
Affinity DataIC50:  280nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclic AMP-dependent transcription factor ATF-1(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062658(3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed