BDBM50062795 3-((S)-4-Carboxymethyl-1-{2-[4-(2-dimethylamino-ethyl)-benzoylamino]-acetyl}-3-oxo-piperazin-2-yl)-propionic acid::CHEMBL422132

SMILES CN(C)CCc1ccc(cc1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CCC(O)=O

InChI Key InChIKey=RLRVAHVRDIDRIV-KRWDZBQOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062795   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062795(3-((S)-4-Carboxymethyl-1-{2-[4-(2-dimethylamino-et...)
Affinity DataIC50:  45nMAssay Description:Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia(HEL) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062795(3-((S)-4-Carboxymethyl-1-{2-[4-(2-dimethylamino-et...)
Affinity DataIC50:  4.20E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062795(3-((S)-4-Carboxymethyl-1-{2-[4-(2-dimethylamino-et...)
Affinity DataIC50:  2.50E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed