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BDBM50062971 CHEMBL3397917

SMILES: COc1ccc(C(=O)Nc2ccc(OCCN3CCCCC3)cc2)c(c1O)-c1cccc(O)c1

InChI Key: InChIKey=ZCZIHRDIJBRCRT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062971   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50062971
PNG
(CHEMBL3397917)
Show SMILES COc1ccc(C(=O)Nc2ccc(OCCN3CCCCC3)cc2)c(c1O)-c1cccc(O)c1
Show InChI InChI=1S/C27H30N2O5/c1-33-24-13-12-23(25(26(24)31)19-6-5-7-21(30)18-19)27(32)28-20-8-10-22(11-9-20)34-17-16-29-14-3-2-4-15-29/h5-13,18,30-31H,2-4,14-17H2,1H3,(H,28,32)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.40n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using ATP measured luminescence by ADP-Glo Kinase assay


Bioorg Med Chem 23: 1044-54 (2015)


Article DOI: 10.1016/j.bmc.2015.01.006
BindingDB Entry DOI: 10.7270/Q218385C
More data for this
Ligand-Target Pair