BDBM50063133 (R)-3-Methyl-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benzenesulfonylamino]-butyric acid::CHEMBL288750

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1nnn(n1)-c1ccccc1)C(O)=O

InChI Key InChIKey=VTEHMCYSJRSGPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063133   

TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063133((R)-3-Methyl-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benz...)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against Matrix metalloprotease-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063133((R)-3-Methyl-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benz...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063133((R)-3-Methyl-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benz...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloprotease-2 MMP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed