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BDBM50063243 CHEMBL161499::N-(2,6-Diisopropyl-phenyl)-2-pyridin-2-yl-malonamic acid dodecyl ester

SMILES: CCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccn1

InChI Key: InChIKey=FLVBUNDCSNJSKV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063243   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063243
PNG
(CHEMBL161499 | N-(2,6-Diisopropyl-phenyl)-2-pyridi...)
Show SMILES CCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccn1
Show InChI InChI=1S/C32H48N2O3/c1-6-7-8-9-10-11-12-13-14-17-23-37-32(36)29(28-21-15-16-22-33-28)31(35)34-30-26(24(2)3)19-18-20-27(30)25(4)5/h15-16,18-22,24-25,29H,6-14,17,23H2,1-5H3,(H,34,35)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair