BDBM50063338 4-(8-Chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid phenyl ester::CHEMBL170860

SMILES Clc1ccc2C(N3CCN(CC3)C(=O)Oc3ccccc3)c3ncccc3C=Cc2c1

InChI Key InChIKey=BNYFULICRAJPCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063338   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063338(4-(8-Chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin...)
Affinity DataIC50:  880nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed