BDBM50063476 (3S,10R,13S)-10,13-Dimethyl-17-[1,2,3]triazol-1-yl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol::CHEMBL78108
SMILES C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C1CC=C2n1ccnn1
InChI Key InChIKey=OKJRJJXKSVCWCZ-KJBVPOJVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50063476
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity for Cytochrome P450 17A1 (17-alpha-hydroxypregnenolone Km=560 nM)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat Cytochrome P450 17A1More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataIC50: 377nMAssay Description:In vitro cytochrome P450 17A1 inhibition was assayed using the rapid acetic acid releasing assay (AARA), utilizing intact P450c17-expressing Escheric...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair