BDBM50063544 1-(6-(methylthio)naphthalen-2-yl)propan-2-amine::1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine::2-Amino-1-(4-methylthiophenyl)propane::CHEMBL6467
SMILES CSc1ccc(CC(C)N)cc1
InChI Key InChIKey=OLEWMKVPSUCNLG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50063544
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:Inhibition of MAOA in rat brain mitochondriaMore data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Inhibition of [3H]5-HT uptake at human SERT expressed in HEK293 cells after 10 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
University Of Chile
Curated by ChEMBL
University Of Chile
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Trinity College
Curated by ChEMBL
Trinity College
Curated by ChEMBL
Affinity DataIC50: 207nMAssay Description:Inhibition of [3H]5-HT reuptake at rat SERT expressed in HEK293 cells after 2 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]5-HT uptake at SERTMore data for this Ligand-Target Pair
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of human dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Trinity College
Curated by ChEMBL
Trinity College
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]5-HT uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Trinity College
Curated by ChEMBL
Trinity College
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]-5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+3nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Trinity College
Curated by ChEMBL
Trinity College
Curated by ChEMBL
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of human noradrenaline transporterMore data for this Ligand-Target Pair